Jesolo is a seaside resort town and comune situated in the Metropolitan City of Venice within the Veneto region of Italy. Located along the Adriatic coast north-east of Venice, between Eraclea and Cavallino-Treporti, it occupies a flat landscape edged by the rivers Sile and Piave. The urbanized area lies on an island-like formation delimited by these rivers and an artificial canal called Cavetta. Jesolo gives its name to a 22-square-kilometer lagoon on the Adriatic Sea, serving as a significant coastal municipality in northern Italy.

In Roman times, the area was part of a lagoon containing several islands, with the largest known as Equilium, meaning town of horses. Jesolo likely represents a corruption of this ancient name. Following barbarian invasions, migration occurred from cities like Altino to safer lagoon islands. Equilio became one of the founding cities of the Duchy of Venice and later the Venetian Republic. It flourished as a diocese seat until environmental decline and patrician movement led to its suppression in 1466.

The town features medieval remains from ancient Equilio, including the Antiche Mura archaeological site with the Santa Maria Assunta cathedral and San Mauro monastery. Modern architecture has transformed the skyline, ranking fifth or sixth in Italy for highrises, with structures like Torre Aquileia reaching 94 meters. Major public gardens include Parco Pegaso, themed after Greek mythology, and Parco Ca' Silis, which bridges the old town with the Lido area along the Sile river.

As a popular destination for foreign tourists and locals, Jesolo offers extensive hotels and shops near its 15-kilometer beach. Cultural attractions include the Military History Museum Vidotto, JMuseo dedicated to contemporary art, and the Civic Museum of Natural History housed within it. The town attracts visitors from Central Europe due to its proximity and sandy coastal strip. It ranks second among Italian beach resorts for visitor numbers and third for nights spent.

The population is 26,558 as of 2023. Access is facilitated by frequent ATVO bus services from Venice Marco Polo Airport, Treviso Canova Airport, and Mestre Railway Station. The nearest railway station is San Donà di Piave. With around 1.3 million visitors annually, the town experiences high tourist pressure, making it one of the fifty Italian towns with the greatest influx relative to its inhabitants.