Puebla de Lillo is a municipality located in the province of León, in the autonomous community of Castile and León, Spain. It is situated in the Liébana region, within the Picos de Europa mountain range. The town is part of the Liébana judicial party and has its own municipal capital.

The municipality of Puebla de Lillo covers an area of 264.15 square kilometers and has a population that varies seasonally due to its rural nature. The economy of the area is primarily based on agriculture and livestock, with some tourism related to its natural beauty. The town's infrastructure includes various smaller settlements and rural areas within its jurisdiction.

Puebla de Lillo is known for its natural surroundings, including mountains, valleys, and rivers that make it a destination for nature lovers and those interested in rural Spanish life. The area offers opportunities for outdoor activities such as hiking and exploring the local flora and fauna. Its remote location contributes to its preservation of traditional ways of life.

The historical and cultural significance of Puebla de Lillo is tied to its role as a rural community within the larger region of Castile and León. The town and its surroundings are dotted with historical buildings, churches, and other landmarks that reflect its past.